{"id":4131,"date":"2020-07-13T11:55:53","date_gmt":"2020-07-13T15:55:53","guid":{"rendered":"https:\/\/www.frontagelab.com\/?page_id=4131"},"modified":"2020-10-30T08:26:24","modified_gmt":"2020-10-30T12:26:24","slug":"2020-ind-enabling-toxicology","status":"publish","type":"page","link":"https:\/\/frontagelab.com.cn\/en\/2020-ind-enabling-toxicology\/","title":{"rendered":"2020 IND Enabling Toxicology"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Thank you for visiting our 2020 IND-Enabling Toxicology Page!<\/h2>\n\n\n\n<p> <a href=\"https:\/\/www.frontagelab.com\/about\/company-overview\/\">Frontage Laboratories<\/a>&nbsp;provides toxicology services to guide new therapies from discovery to full development support.&nbsp; Our extensive profile of IND enabling pivotal studies support swift progression of your lead compounds into the clinic \u2013 streamlining your development process.&nbsp; We provide the resources of a highly skilled, client-focused staff with extensive academic, scientific and pharmaceutical industry experience. <\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>IND-enabling studies<br><\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\"><li>Regulatory\/general toxicity<ul><li>Maximum tolerated dose<\/li><li>Dose range-finding \u2013 5-14 days<\/li><li>Single and repeat-dose GLP<\/li><li>Rodents, dogs, NHP, minipig<\/li><li>Complete toxicokinetics support with LC-MS\/MS<\/li><\/ul><\/li><li>Safety pharmacology<ul><li>ICH core battery: CV, CNS, respiratory<\/li><li>Supplemental studies: renal, GI<\/li><\/ul><\/li><li>Full clinical and anatomic pathology, ophthalmology, ECG<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>For more information, visit <a href=\"https:\/\/www.frontagelab.com\/service\/toxicology\/\">https:\/\/www.frontagelab.com\/service\/toxicology\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thank you for visiting our 2020 IND-Enabling Toxicology Page! Frontage Laboratories&nbsp;provides toxicology services to guide new therapies from discovery to&#8230;<\/p>\n","protected":false},"author":30,"featured_media":4709,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4131","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/frontagelab.com.cn\/en\/wp-json\/wp\/v2\/pages\/4131"}],"collection":[{"href":"https:\/\/frontagelab.com.cn\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/frontagelab.com.cn\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/frontagelab.com.cn\/en\/wp-json\/wp\/v2\/users\/30"}],"replies":[{"embeddable":true,"href":"https:\/\/frontagelab.com.cn\/en\/wp-json\/wp\/v2\/comments?post=4131"}],"version-history":[{"count":0,"href":"https:\/\/frontagelab.com.cn\/en\/wp-json\/wp\/v2\/pages\/4131\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/frontagelab.com.cn\/en\/wp-json\/wp\/v2\/media\/4709"}],"wp:attachment":[{"href":"https:\/\/frontagelab.com.cn\/en\/wp-json\/wp\/v2\/media?parent=4131"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}