Oligonucleotide (OGN) therapy is increasingly recognized as an important therapeutic modality on the promise of curing diseases. However, unlike most biotherapeutics, the development of OGN drugs often requires their determination with high sensitivity and specificity in multiple and complex biologic matrices such as blood and tissues in order to measure their exposure and distribution for understating PK, PD and safety.
在方达我们已经开发出了高度灵敏和特异性的定量方法,使用杂交免疫测定法和LC-MS技术测定血浆和组织中的OGN。在本网络研讨会中,我们将介绍OGN定量方法的开发,验证和这些技术的比较,以及反义寡核苷酸的案例研究。
下载报名
提交注册以获得对内部资源的访问权限。