DMPK

Proven techniques and best-in-class approaches

Laboratory Services
Product Development
Clinical Services
Applications and Solutions

DMPK

At Frontage, our scientific staff applies proven techniques and best-in-class approaches to generate data for critical milestones and decision making during drug discovery and development.

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The highly trained and experienced scientific team provides broad and in-depth expertise/advice to clients on appropriate study designs, execution of studies, and interpretation of the data. We offer extensive drug metabolism and pharmacokinetic capabilities for new chemical entities and compounds in development.

  • Structural Optimization in Early Discovery
  • Pharmacokinetic Studies in Rodents, Dogs, NHP, Rabbits, and Mini-Pigs
  • In Vitro ADME (Discovery & Development)
  • Non-GLP Bioanalytical Studies
  • Radiolabel Studies (including Mass Balance)

For pharmaceuticals, we conduct a range of in vivo and in vitro ADME studies that are needed for selecting lead drug candidates in discovery or are required for regulatory filings of potential therapeutic agents. A range of capabilities and experience exist at Frontage to support discovery and development of drug candidates

For agrochemicals, we offer residual analyses, syntheses of metabolite standards and GLP in vivo/in vitro[jb1]  studies with radiolabeled compounds. For more information on our Agrochemical capabilities

FACT: Provide Scientific input to influence selection of lead drug candidates

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