Agrochemical

In vitro and in vivo studies in support of compound registration.

Agrochemical

Frontage Laboratories provides extensive support to clients in the Agrochemicals industry. Our broad service offering includes biological, chemical, and regulatory support in a GLP-compliant facility.

Residue Chemistry

• Field soil dissipation
• Magnitude of the residue
• Crop field trials & storage stability
• Livestock feeding studies (cattle, poultry)
• Analytical methods development
• Independent Laboratory Validations (ILV)

Metabolism

  • Plant Metabolism
    • Metabolite identification
    • Metabolite (cold) synthesis
    • Distribution studies
    • Reincorporation methodology (14C)
    • Greenhouse Facilities
  • Animal Absorption, Distribution, Metabolism and Excretion
    • Radiolabeled and non-labeled compounds
    • Single and multiple dose studies
    • Multiple species (mice, rats, dogs, monkeys, minipigs)
    • Oral, dermal, IP, SQ, IV
    • Special surgical techniques
    • Bile duct/hepatic portal vein
    • Metabolite identification/quantitation
    • Nature of the residue studies

Environmental Fate

  • Degradation (hydrolysis, photodegradation)
    • Aerobic and anaerobic metabolism (soil, aquatic)
    • Mobility (absorption/desorption, soil column leaching)
  • Fish bioaccumulation (metabolite identification)
    • Analytical Support
  • Confined accumulation (rotational crop)
  • Field rotational crop
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