Assays

Donafenib Tosylate -

(Matrix: Human Plasma)

Analytes:

Donafenib Tosylate

Matrix:

Human Plasma

Assay Range:

5-5000 ng/mL

Sample Volume:

50 µL

Anticoagulant:

Sodium Heparin

StorageTemp (oC):

-80

Platform:

LC-MS/MS

Donepezil -

(Matrix: Human Plasma)

Analytes:

Donepezil

Matrix:

Human Plasma

Assay Range:

0.1-30 ng/mL

Sample Volume:

50 µL

Anticoagulant:

K2EDTA

StorageTemp (oC):

-20

Platform:

LC-MS/MS

Donepezil -

(Matrix: Human Plasma)

Analytes:

Donepezil

Matrix:

Human Plasma

Assay Range:

0.1-50 ng/mL

Sample Volume:

200 µL

Anticoagulant:

K2EDTA

StorageTemp (oC):

-20

Platform:

LC/MS/MS

Donepezil -

(Matrix: Human Plasma)

Analytes:

Donepezil

Matrix:

Human Plasma

Assay Range:

0.1-50 ng/mL

Sample Volume:

200 µL

Anticoagulant:

K2EDTA

StorageTemp (oC):

-20

Platform:

LC-MS/MS

Donepezil -

(Matrix: Human Plasma)

Analytes:

Donepezil

Matrix:

Human Plasma

Assay Range:

0.2-20 ng/mL

Sample Volume:

50 µL

Anticoagulant:

Sodium Heparin

StorageTemp (oC):

-20/-70/-80

Platform:

LC-MS/MS

Doripenem -

(Matrix: Human CSF)

Analytes:

Doripenem

Matrix:

Human CSF

Assay Range:

20- 5000 ng/mL

Sample Volume:

25 µL

Anticoagulant:

NA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doripenem / Doripenem Dicarboxylic Acid -

(Matrix: Human Plasma)

Analytes:

Doripenem / Doripenem Dicarboxylic Acid

Matrix:

Human Plasma

Assay Range:

0.1/0.1- 50/50 µg/mL

Sample Volume:

25 µL

Anticoagulant:

Heparin

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doripenem / Doripenem Dicarboxylic Acid -

(Matrix: Human Urine)

Analytes:

Doripenem / Doripenem Dicarboxylic Acid

Matrix:

Human Urine

Assay Range:

0.2/0.2- 100/100 µg/mL

Sample Volume:

100 µL

Anticoagulant:

NA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin -

(Matrix: Human Plasma)

Analytes:

Doxorubicin

Matrix:

Human Plasma

Assay Range:

1 -1000 ng/mL

Sample Volume:

50 µL

Anticoagulant:

K2EDTA

StorageTemp (oC):

-20

Platform:

LC-MS/MS

Doxorubicin -

(Matrix: Rat Heart/ Lung/Kidney/Liver/Spleen)

Analytes:

Doxorubicin

Matrix:

Rat Heart/ Lung/Kidney/Liver/Spleen

Assay Range:

50- 5000 ng/g

Sample Volume:

10mg

Anticoagulant:

NA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin -

(Matrix: Mouse Heart/ Lung/Kidney/Liver/Spleen)

Analytes:

Doxorubicin

Matrix:

Mouse Heart/ Lung/Kidney/Liver/Spleen

Assay Range:

80- 40000 ng/g

Sample Volume:

6.25mg

Anticoagulant:

NA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin -

(Matrix: Human Plasma)

Analytes:

Doxorubicin

Matrix:

Human Plasma

Assay Range:

1 -1000 ng/mL

Sample Volume:

50 µL

Anticoagulant:

K2EDTA

StorageTemp (oC):

-20

Platform:

LC/MS/MS

Doxorubicin / Doxorubicinol -

(Matrix: Rat Skin/Spleen, bone marrow, lung, testes, kidney/liver/Heart)

Analytes:

Doxorubicin / Doxorubicinol

Matrix:

Rat Skin/Spleen, bone marrow, lung, testes, kidney/liver/Heart

Assay Range:

50/20- 5000/2000 ng/g

Sample Volume:

5mg

Anticoagulant:

NA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin (free) -

(Matrix: Human Plasma)

Analytes:

Doxorubicin (free)

Matrix:

Human Plasma

Assay Range:

1- 1000 ng/mL

Sample Volume:

50 µL

Anticoagulant:

EDTA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin (free) /Doxorubicinol -

(Matrix: Rat Plasma)

Analytes:

Doxorubicin (free) /Doxorubicinol

Matrix:

Rat Plasma

Assay Range:

1/0.5- 1000/250 ng/mL

Sample Volume:

50 µL

Anticoagulant:

EDTA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin (free)/Doxorubicinol -

(Matrix: Human Plasma)

Analytes:

Doxorubicin (free)/Doxorubicinol

Matrix:

Human Plasma

Assay Range:

1/0.5-600/20 ng/mL

Sample Volume:

200 µL

Anticoagulant:

K2EDTA

StorageTemp (oC):

-20

Platform:

LC-MS/MS

Doxorubicin (liposomal encap) -

(Matrix: Rat Plasma)

Analytes:

Doxorubicin (liposomal encap)

Matrix:

Rat Plasma

Assay Range:

10- 10000 ng/mL

Sample Volume:

22 µL

Anticoagulant:

EDTA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin (liposomal encap) -

(Matrix: Mouse Plasma)

Analytes:

Doxorubicin (liposomal encap)

Matrix:

Mouse Plasma

Assay Range:

10 - 10000 ng/mL

Sample Volume:

11 µL

Anticoagulant:

EDTA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin (liposomal encap) -

(Matrix: Human Plasma)

Analytes:

Doxorubicin (liposomal encap)

Matrix:

Human Plasma

Assay Range:

10 - 10000 ng/mL

Sample Volume:

220 µL

Anticoagulant:

EDTA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin (Total )/Doxorubicinol -

(Matrix: Mouse Liver Mouse Spleen Mouse Tumor)

Analytes:

Doxorubicin (Total )/Doxorubicinol

Matrix:

Mouse Liver Mouse Spleen Mouse Tumor

Assay Range:

50/10- 5000/1000 ng/g

Sample Volume:

10 mg

Anticoagulant:

NA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin (total) -

(Matrix: Rat Plasma)

Analytes:

Doxorubicin (total)

Matrix:

Rat Plasma

Assay Range:

0.5-50 µg/mL

Sample Volume:

22 µL

Anticoagulant:

EDTA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

Doxorubicin (total) -

(Matrix: Mouse Plasma)

Analytes:

Doxorubicin (total)

Matrix:

Mouse Plasma

Assay Range:

0.5-150 µg/mL

Sample Volume:

22 µL

Anticoagulant:

EDTA

StorageTemp (oC):

-20/-70

Platform:

LC-MS/MS

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